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Synced Nov 12 11:45 ET PHPreHealth
Agency workspace

Setup

Connectors

What PreListen tracks for Conexeu Sciences. Read from src/data/clients/conexeu/client.json; change it there and run a refresh.

Key takeaway

PreListen tracks 14 brands, 6 category topics and 8 target AI queries for Conexeu Sciences. 5 of 9 sources are read automatically; 4 are not.

Supporting data
  • 14 brands in 4 rings, one Google News query each
  • 6 category topics, one query each
  • 5 claims-scan rules run on every conexeu.com page
  • 8 of 13 KPIs computed today
What we’re doing

Connect the 4 sources that need keys or client OAuth: Social profiles, AI engines, Google Search Console + GA4, LinkedIn + Instagram (owned).

Client profile

Hand-kept in the profile file; every field is sourced.

conexeu.com
Legal name
Conexeu Sciences Inc.
Ticker
Nasdaq: CNXU · listed May 21 2026
Product
CXU · Thermosensitive flowable collagen scaffold (Ten-Minute Tissue)
Category
Regenerative tissue platform
Positioning
Architecting Bioregeneration. Regeneration fails for want of structure; CXU supplies the structure.
Status
CXU is an investigational medical device candidate in preclinical development. It has not been submitted to or reviewed by the U.S. Food and Drug Administration. Safety and effectiveness have not been established.
Milestone
510(k) premarket notification, lead wound-care candidate: Planned Q1 2027
Verticals
Wound care · LeadAesthetics · LoudestOral health · NamedAnimal health · Option3D bioprinting and breast reconstruction · Narrative
Profile sourcesLinkAs of
Conexeu Knowledge System
knowledgeconexeu-knowledge.vercel.app/Aug 22 2026
Conexeu Social & Search Plan, rev 1
planconexeu-social-search-plan.vercel.app/Aug 20 2026
conexeu.com
sitewww.conexeu.comlive site

Tracked brands

Each brand is one Google News query (shown exactly as sent), and a headline counts for a brand only when it matches the brand’s pattern.

Competitors

Client 1

Conexeu Sciences’s own name, ticker and product

BrandGoogle News queryHeadline must match30 days
Conexeu
conexeu.com "Conexeu" OR "CNXU" /\bConexeu\b|\bCNXU\b|Ten-Minute Tissue/i 13

Ring 1 · Structural analogs 7

Compete for the same clinical job: giving host cells a structure to populate.

BrandGoogle News queryHeadline must match30 days
Aroa Biosurgery
ECM bioscaffolds · aroa.com "Aroa Biosurgery" OR "Myriad Matrix" /\bAroa\b|Myriad Matrix|Endoform/i 13
Integra LifeSciences
Wound care, flowable · integralife.com "Integra LifeSciences" /Integra Life ?Sciences|\bIART\b|Integra (?:Flowable|Dermal|wound)/i 25
MiMedx
Wound care biologics · mimedx.com "MiMedx" /\bMiMedx\b|\bMDXG\b/i 23
Organogenesis
Advanced wound care · organogenesis.com "Organogenesis" /\bOrganogenesis\b|\bORGO\b/i 23
Sanara MedTech
Wound care, flowable ECM · sanaramedtech.com "Sanara MedTech" /\bSanara\b|\bSMTI\b/i 8
MTF Biologics (Renuva)
Allograft adipose matrix · mtfbiologics.org "MTF Biologics" OR "Renuva" /MTF Biologics|\bRenuva\b/i 0
Kerecis (Coloplast)
Biologic wound care · kerecis.com "Kerecis" /\bKerecis\b/i 3

Ring 2 · Category owners 4

Compete for the same attention and injector relationships, with results content.

BrandGoogle News queryHeadline must match30 days
Galderma
Aesthetics: Sculptra, Restylane · galderma.com "Galderma" OR "Sculptra" /\bGalderma\b|\bSculptra\b|\bRestylane\b/i 24
Allergan Aesthetics
Aesthetics: Juvederm · allerganaesthetics.com "Allergan Aesthetics" OR "Juvederm" /Allergan Aesthetics|Juv[eé]derm/i 9
Merz Aesthetics
Aesthetics: Radiesse · merzaesthetics.com "Merz Aesthetics" OR "Radiesse" /Merz Aesthetics|\bRadiesse\b|\bXeomin\b/i 6
Evolus
Aesthetics: Jeuveau, Evolysse · evolus.com "Evolus" /\bEvolus\b|\bJeuveau\b|\bEvolysse\b/i 26

Ring 3 · Narrative peers 2

Compete for the future story: who gets believed about what regeneration will be.

BrandGoogle News queryHeadline must match30 days
CollPlant
Recombinant collagen, bioprinted breast implants · collplant.com "CollPlant" /\bCollPlant\b|\bCLGN\b/i 22
Establishment Labs
Breast aesthetics and reconstruction · establishmentlabs.com "Establishment Labs" OR "Motiva implants" /Establishment Labs|\bMotiva\b/i 27

Category topics

Conversations Conexeu Sciences can join without a product claim. One Google News query per topic; a headline joins a topic when it matches the pattern.

Coverage
Topic, angle and formatGoogle News queryHeadline must match90 days
Breast reconstruction beyond implants
Angle: Regenerate, don't replace. Format: CSO first-person post on B.R.E.A.S.T. at Wake Forest. "breast reconstruction" /breast/i 76
GLP-1 skin and volume loss
Angle: the structural argument: GLP-1 loss is architecture, not just volume. Format: GLP-1 seven-slide carousel. "Ozempic face" OR "GLP-1" aesthetic OR "GLP-1" skin /Ozempic face|GLP-?1|semaglutide|tirzepatide|Wegovy|Mounjaro|weight[- ]loss/i 46
Extracellular matrix and scaffolds
Angle: what an ECM scaffold is, in plain language. Format: Mechanism film: the view from under the skin. "extracellular matrix" OR "collagen scaffold" /extracellular matrix|\bECM\b|scaffold|collagen matrix/i 20
Flowable wound matrices and 510(k)
Angle: the wound-care path and what a 510(k) does and does not mean. Format: CMO explainer on the wound-care pathway. "skin substitute" OR "wound matrix" OR "flowable matrix" /wound|skin substitute|510\(k\)|LCD/i 22
Biostimulators and regenerative aesthetics
Angle: occupy, provoke, structure: the three mechanism classes. Format: Filler vs biostimulator vs scaffold explainer. biostimulator OR "regenerative aesthetics" /biostimulat|regenerative aesthetic|collagen[- ]stimulat|Sculptra|Radiesse|polynucleotide/i 13
Dermal filler safety and regulation
Angle: why structure, not volume, is the conversation to have. Format: Unbranded category education post. "dermal filler" OR "dermal fillers" /filler/i 20

Target AI queries

The queries Conexeu Sciences should be the cited answer for, from the Conexeu Social & Search Plan, rev 1. Not sampled yet: needs api keys.

AI Search
QuerySurfaceWho owns it todayWhat we want the answer to say
What causes Ozempic face?AI + GoogleDermatology practices and journalsThe structural framing: subcutaneous adipose architecture, not surface volume.
How do you treat GLP-1 facial volume loss?AI + GoogleHA filler content, consensus guidanceThe third category. The query the seven-slide carousel is built for.
What is an extracellular matrix scaffold?AIPeer-reviewed literaturePlain-language definition with a named example.
Alternative to fat graftingGoogle + TikTokRenuva and practice blogsMechanism-level entry, not a product claim.
Filler vs biostimulator vs scaffoldAI + Instagram searchNobodyThe three-way comparison does not exist yet. Cleanest unclaimed query.
3D bioprinted breast reconstructionAI + GoogleCollPlant, academic groupsB.R.E.A.S.T. and the Wake Forest programme, told by the CSO.
Is there an alternative to breast implants?Google + TikTokSurgical practicesRegenerate, don't replace.
Conexeu Sciences / CNXUAllSplit between conexeu.com and ir.conexeu.comBlocked until the Organization schema and legal-name string are settled.

Science and regulatory queries

Sent as written to PubMed, ClinicalTrials.gov and openFDA.

Science & FDA
SourceQuerySearch
PubMedGhahary lab (UBC) collagen papersGhahary A[au] AND (collagen OR scaffold OR wound)
PubMedECM in regenerative aesthetics(extracellular matrix[tiab] OR collagen scaffold[tiab]) AND (aesthetic*[tiab] OR facial[tiab] OR soft tissue augmentation[tiab])
PubMedFlowable collagen in wound care(flowable[tiab] OR injectable[tiab] OR thermosensitive[tiab]) AND collagen[tiab] AND wound*[tiab]
PubMedGLP-1 and facial soft tissue(semaglutide[tiab] OR tirzepatide[tiab] OR GLP-1[tiab]) AND (facial[tiab] OR skin laxity[tiab] OR soft tissue[tiab])
ClinicalTrials.govFlowable and injectable wound matricesflowable wound matrix OR injectable collagen wound
ClinicalTrials.govECM and collagen fillers in aestheticscollagen filler OR biostimulator OR extracellular matrix aesthetic
ClinicalTrials.govRegenerative breast reconstructionbreast reconstruction regenerative OR bioprinted breast
openFDACollagen wound dressings and flowable matricesdevice_name:(flowable AND (wound OR matrix)) OR (device_name:collagen AND device_name:(wound OR matrix OR dressing))

Alert rules

The rules that turn signals into the Plan of action on Pulse. Each action is scored for impact and urgency; the four highest are High priority and appear under the bell in the top bar. Scores of 7 or more are Medium, the rest Low.

Plan of action
Rule and what it asks forAction kindFires whenFiring now
Trending category topic
Write a post on the topic’s angle, in the approved register, with the status line in the copy. Post A tracked topic has at least 3 headlines in the last 3 weeks and runs at 1.25× or more its weekly average over the 9 weeks before. 5 · 4 high
Fresh coverage of the client
Turn it into a first-person post from a named person. Post A headline naming Conexeu Sciences in the last 14 days that is not a markets item. Up to 2 at a time. 2
Competitor velocity
Brief the team. Never answer with a comparative claim (R5). Prepare A competitor has at least 2 headlines in 7 days and runs at 2× or more its usual week (its average over the 11 weeks before). The 2 fastest. 2
Claims findings
Review the passages on Compliance with client counsel. Fix Any passage on conexeu.com matches a claims-scan rule. One action per rule. 3
Site defects
Unpublish or finish the page; add the schema; rewrite descriptions; fix the heading tree. Fix · Optimize An unfinished (“in work”) page is publicly reachable; no Organization structured data; pages share a meta description; pages render several H1s. 1
No AI-answer baseline
Connect the AI engines and take a baseline. Decide The 8 target AI queries have never been sampled. Fires until the AI engines are connected. 1
Social profile gaps
Open or reserve the channel; connect LinkedIn and Instagram. Optimize · Decide An owned channel has no handle, or the hand-read social figures are more than 30 days old. 2
New research
An unbranded clinician explainer. Create A paper in the tracked PubMed queries dated in the last 60 days. The newest one. 1
Comparable 510(k) decision
Add it to the comparables list. Prepare An openFDA 510(k) decision for a comparable device in the last 180 days. The latest one. 1
Open decision
Get the named owner to decide; dependent content waits. Decide Each open decision logged in the Conexeu Knowledge System. 5
Delivery is in the app only: the Plan of action, the bell (4 high priority now) and My plan. No email, Slack or SMS routing is set up. Action kinds: Post (publish on owned social while the topic is moving); Create (make a page or asset that answers demand nobody owns yet); Respond (reply to or correct something said about the client); Pitch (earned media, partner or kol outreach); Optimize (improve an existing page or profile); Fix (correct a defect or a claims risk on an owned surface); Prepare (get ahead of a competitor or regulatory move); Decide (needs a person to decide or approve).

Claims rules

The rules every piece of CXU content follows, and the patterns the crawl tests conexeu.com against.

Compliance
RuleWhat it saysDetail
R1No outcome claimsNothing that says or implies CXU regenerates, restores, heals, works or performs.
R2No results and no performance numbersNo percentages, no timelines to benefit, no efficacy data, and no animal-study result presented as human benefit.
R3No before-and-afterIn any form: photography, illustration, slider, animation, day 0 and day 90.
R4No testimonial as evidenceA quote may describe the approach. It may not attest to results.
R5No comparative claims against a named competitor productCompetitor marks carry the registered symbol and the no-affiliation disclaimer wherever they appear.
R6Status disclosure travels with the claimAt first substantive mention, not only in a footer. On social, in the post copy itself.
R7Superlatives are caveatednext-generation, advanced, innovative and bioregenerative only with the IMPORTANT NOTICES caveat in the same communication.
R8Forward-looking statementsFuture milestones, submissions, markets or financing must reference the Forward-Looking Cautionary Statement.

Website scan patterns

ScanRulePattern (case-insensitive)Findings
Retired or prohibited term Scrub list \bMeshFill\b|\babiologic\b|no growth factors|no cytokines|human cell[- ]derived|commercially viable|freedom to operate|CollPlant 0
Outcome verb R1 \b(?:heals|restores|regenerates|proven to|clinically proven|cures?)\b 3
Performance number R2 \d+(?:\.\d+)?\s?% (?:faster|closure|improvement|reduction|increase)|\b\d+% wound closure|by day \d+ 0
Approval language R1/R6 \b(?:FDA[- ]approved|FDA[- ]cleared|approved for|cleared for)\b 3
Uncaveated superlative R7 \b(?:next[- ]generation|revolutionary|breakthrough|first[- ]of[- ]its[- ]kind|best[- ]in[- ]class)\b 21

Negations (“has not been approved for”) are skipped for every scan except the scrub list. Header, navigation and footer text are not scanned.

KPI definitions

Every page, widget and report uses these formulas. A KPI that is not connected shows no figure anywhere.

Pulse

HeadlinesLive
Google News items in the window whose headline names the brand Counted from: Google News RSS, one query per brand Caveat: Syndicated copies of one headline count once. Stories that cover a brand without naming it in the headline are not counted.
Share of news voiceLive
Brand headlines ÷ headlines naming any tracked brand Counted from: Headlines Caveat: Ring 2 aesthetics majors carry far more news than preclinical companies; read it alongside the ring view on Competitors.
Topic momentumLive
Topic headlines per week over the last 3 weeks ÷ the weekly average of the 9 weeks before Counted from: Google News RSS, one query per topic Caveat: A topic counts as trending at 1.25× or more with at least 3 headlines in the last 3 weeks.
FollowersNot connected
Followers on each owned channel Counted from: Read by hand from the live profiles; live once LinkedIn and Instagram are connected Caveat: Dated snapshot. Shows the read date next to every figure.

Competitors

VelocityLive
Headlines in the last 7 days ÷ the brand’s average week over the 11 weeks before Counted from: Headlines Caveat: Shown only for brands averaging at least one headline every two weeks.
Engagements per 1,000 followersNot connected
(reactions + comments) ÷ followers × 1,000 Counted from: Read by hand from the live posts

Compliance

Claims findingsLive
Distinct passages on the client’s website that match a claims-scan rule; the same passage on many pages counts once Counted from: Sitemap crawl + the client’s claims register Caveat: A finding is a passage to review, not a confirmed violation. Negations such as “has not been approved for” are skipped.

Search

Site issuesLive
Pages missing a meta description, canonical or structured data, sharing a description, or with no or several H1s Counted from: Sitemap crawl
Organic visibilityNot connected
Σ(CTR at rank × volume) ÷ Σ volume, tracked keyword set Counted from: Needs Google Search Console

Science

New papersLive
PubMed records in each research query with a publication date in the last 12 months Counted from: PubMed E-utilities
510(k) decisionsLive
openFDA 510(k) decisions for comparable collagen and flowable wound devices in the last 3 years Counted from: openFDA device API

AI Search

AI visibilityNot connected
Answers naming the brand ÷ sampled answers × 100, per target query Counted from: Needs ChatGPT, Gemini, Perplexity and Claude API keys and a SERP provider

Coverage

Net sentimentNot connected
(positive − negative) ÷ all mentions × 100 Counted from: Needs the sentiment classifier and a labelled set for this client

How to refresh

Snapshots are re-read from the public sources by a script; no API keys needed. Every production build runs it first, keeping the previous snapshot for any source that fails.

npm run refreshEvery client, every source. Fails loudly if a source fails.
node scripts/refresh.mjs conexeu newsOne client, one source: news, research, trials, fda or site.
node scripts/refresh.mjs --softKeep the previous snapshot for anything that fails (what the build uses).
SnapshotCoversLast read
Google NewsHeadlines for 14 brands and 6 topics, 90 daysNov 12
conexeu.com crawl62 sitemap pages: SEO basics and the claims scanNov 12
PubMed4 research queries, newest papersNov 12
ClinicalTrials.gov3 study queriesNov 12
openFDA510(k) decisions for comparable devices, 3 yearsNov 12
Social profilesFollowers and post engagement, read by handAug 20 · by hand

How to add a client

A client is a folder. The app finds it at build time; nothing else is registered.

  1. Create the folder src/data/clients/<slug>/. The slug becomes the URL: /c/<slug>/pulse.
  2. Write client.json with the same shape as src/data/clients/conexeu/client.json: name, legal name, domain and sitemap, status, brands (one marked isClient, each with a ring, a Google News query and a match pattern), rings, topics, target AI queries, research, trial and FDA queries, the social read, the claims register, rules and scan patterns, and open decisions. Source every field.
  3. Run node scripts/refresh.mjs <slug>. It writes news.json, research.json, trials.json, fda.json and site.json next to the profile.
  4. Check the client switcher. The new client appears in the menu at the top of the navigation, with every page computed from its own snapshots.