Ghahary lab (UBC) collagen papers
0 12 months1 3 yearsGhahary A[au] AND (collagen OR scaffold OR wound) Science & FDA
New research, clinical studies and FDA 510(k) decisions in the lanes CXU competes in. Read from PubMed, ClinicalTrials.gov and openFDA.
Key takeaway
Flowable collagen in wound care is the busiest research lane, with 164 papers in 12 months. FDA made 3 comparable 510(k) decisions in the last 6 months, ahead of Conexeu Sciences’ own 510(k) premarket notification, planned Q1 2027.
Supporting data
- 377 papers in 12 months across 4 research queries
- 33 recent: dated within 60 days of the read
- 252 registered studies across 3 queries
- 11 comparable 510(k) decisions in 3 years, 3 in 6 months
What we’re doing
Turn the newest paper into an unbranded clinician explainer, and keep the 510(k) comparables list current for the submission.
Conexeu Sciences regulatory status
CXU: Thermosensitive flowable collagen scaffold (Ten-Minute Tissue)
CXU is an investigational medical device candidate in preclinical development. It has not been submitted to or reviewed by the U.S. Food and Drug Administration. Safety and effectiveness have not been established.
Status line (rule R6): it travels with every mention of CXU. Copy it as written.
Next milestone 510(k) premarket notification, lead wound-care candidate Planned Q1 2027 Source: Conexeu Knowledge System, Aug 22
Research
PubMed E-utilities, read Nov 12, 2026. Newest papers per query, linked to PubMed. 6 papers carry a date after the read: PubMed lists the journal issue date, which can be ahead of online publication.
ECM in regenerative aesthetics
139 12 months241 3 years(extracellular matrix[tiab] OR collagen scaffold[tiab]) AND (aesthetic*[tiab] OR facial[tiab] OR soft tissue augmentation[tiab]) - In situ ECM-functionalized hyaluronic acid/dextran composite hydrogels for regenerative soft tissue reconstruction. PMID 42887182 Recent
- Obesity, Weight Loss, and Facial Plastic Surgery. PMID 42869738 Recent
- The Skin-Mood Axis in Midlife: Neuro-Immuno-Endocrine Cross-Talk in Perimenopausal and Menopausal Aesthetic Dermatology. PMID 43013592 Recent
- Larsen syndrome of La Reunion Island (B4GALT7-linkeropathy): recommendations for follow-up in the early years of life. PMID 43008968 Recent
- Influence of Microsphere-to-Hydrogel Matrix Composition on Long-Term Volume Retention and Host Tissue Remodeling of Injectable Composite Collagen Hydrogels. PMID 43006852 Recent
- Innovation With Dermal Fillers: HA-CaHA. PMID 42993187 Recent
- Hallmarks of Aesthetic Ageing: A Proposed Tissue-Level Framework for Facial Aging and Precision Regenerative Aesthetics. PMID 42968556 Recent
- Electro-Aesthetic Regulation Enabled by Piezoelectric Signaling. PMID 42945434 Recent
- Microneedling Combined With Biomimetic Peptides for Burn Scar Improvement: A Prospective Study. PMID 42903302 Recent
- Potential Mechanobiological Consequences of Injectable Aesthetic Procedures: Dermal Fillers, Botulinum Toxin, ECM Dynamics, Lymphovascular Drainage, and the Concept of Mechanical Silence. PMID 42939074 Recent
- Deciphering keloid formation and treatment: insights from mechanobiology. PMID 42504714 Recent
- Molecular modulation of cartilage graft survival: a systematic review and translational synthesis of local and systemic strategies. PMID 42725065
Flowable collagen in wound care
164 12 months337 3 years(flowable[tiab] OR injectable[tiab] OR thermosensitive[tiab]) AND collagen[tiab] AND wound*[tiab] - Multifunctional hydrogel assembled from phenylboronic acid-chitosan and Polygonati Rhizoma polysaccharide for accelerated radiation-combined wound healing. PMID 42822316 Recent
- pH-responsive hydrogel delivery of Lycium barbarum glycopeptide coordinates immune-matrix crosstalk to enhance wound healing. PMID 42878251 Recent
- Alveolar Bone Regeneration Using 3D-Printed, Patient-Specific, Resorbable PCL Scaffold: Prospective Cohort Study. PMID 42710893 Recent
- An injectable self-healing hydrogel with cytokine-regulating and antioxidant activities for accelerating diabetic wound repair. PMID 42935466 Recent
- A ROS-Responsive Injectable Hydrogel Platform Reprograms the Diabetic Wound Microenvironment to Enable Exosome Therapy. PMID 42985724 Recent
- Injectable plant vesicles-biomineralized ZnO(2) hydrogel for synergistic chemodynamic antibacterial, anti-inflammatory, and regenerative treatment of infected diabetic wounds. PMID 42727671 Recent
- Bioactive injectable sulfated alginate-based hydrogels containing desferrioxamine for diabetic wound healing. PMID 42710768 Recent
- Oxidized pullulan/carboxymethyl chitosan hydrogel with salidroside for enhanced wound healing. PMID 42702325 Recent
- Carboxymethyl chitosan-based multifunctional hydrogel loaded with ginseng stem cell exosomes promotes severe burn wound healing through anti-inflammatory activity. PMID 42407283 Recent
- Multifunctional antibacterial intelligent hydrogel for infection detection and inflammation regulation to promote diabetic wound healing. PMID 42184751 Recent
- Synergistic Berberine/Pirfenidone-Loaded Thermosensitive Hydrogel: Integrated Antibacterial Defense Activity and Pirfenidone-Mediated Angiogenesis for Efficient Diabetic Wound Repair. PMID 42954794 Recent
- pH-responsive injectable hydrogel dressing integrating antibacteria, antioxidation, anti-inflammation, and angiogenesis for infected wound healing. PMID 42404727
GLP-1 and facial soft tissue
74 12 months98 3 years(semaglutide[tiab] OR tirzepatide[tiab] OR GLP-1[tiab]) AND (facial[tiab] OR skin laxity[tiab] OR soft tissue[tiab]) - Bariatric Surgery, Medical Weight Loss, and the Upper Aerodigestive Tract. PMID 42810933 Recent
- Resistance exercise to attenuate lean mass loss during tirzepatide therapy for obesity: a randomized controlled trial. PMID 43003902 Recent
- Panniculectomy With Umbilical Transposition in the Era of Glucagon-Like Peptide-1 Receptor Agonists: The Impact of Weight Loss Modality on Postoperative Outcomes. PMID 42997336 Recent
- Do Glucagon-Like Peptide-1 Receptor Agonists Sabotage Fat Grafts?: A Scoping Review of Glucagon-Like Peptide-1 Receptor Agonist Effects on Adipocyte Biology and Implications for Autologous Fat Transfer. PMID 42219269 Recent
- Glucagon-Like Peptide-1 Receptor Agonist-Associated Facial Changes: A Comprehensive Review of Pathophysiology, Clinical Manifestations, Risk Factors, Prevention, and Management. PMID 42872378 Recent
- Energy-Based Devices for GLP-1 Receptor Agonist-Associated Facial Aging: A Tissue-Specific Safety Framework. PMID 42893183 Recent
- Beyond Weight Loss: Facial Remodeling Associated with GLP-1 Receptor Agonists-A Systematic Review and Therapeutic Framework. PMID 42864543 Recent
- Adverse Oral and Salivary Effects Associated With Glucagon-Like Peptide-1 Receptor Agonists: Clinical Insights. PMID 42843413 Recent
- Glucagon-like peptide-1 receptor agonists and aesthetic surgery: perioperative safety, timing, durability and body composition. PMID 42898660 Recent
- Effects of GLP-1 receptor agonists on aesthetic surgery practice: A contemporary review. PMID 42830623 Recent
- Implications of Glucagon-Like Peptide-1 Receptor Agonists in Otolaryngology - Head and Neck Surgery: A Review. PMID 42126155 Recent
- Aesthetic, muscle, and dermatologic effects of medical weight management: patient-reported outcomes shape a holistic preventive procedural approach. PMID 42639588
Flowable collagen in wound care is the busiest lane: 164 papers in 12 months, 337 in 3 years.
33 papers across the 4 queries are dated within 60 days of the read.
Ghahary lab (UBC) collagen papers: no paper in 12 months.
Action items
1Explain “In situ ECM-functionalized hyaluronic acid/dextran compos…” for clinicians
2Explain “Obesity, Weight Loss, and Facial Plastic Surgery.” for clinicians
3Explain “Bariatric Surgery, Medical Weight Loss, and the Upper Aer…” for clinicians
Clinical studies
ClinicalTrials.gov API v2, read Nov 12, 2026. Registered studies matching each query, most recently updated first. A match on the query is not a judgement that the study is comparable.
Flowable and injectable wound matrices
160 studies registeredflowable wound matrix OR injectable collagen wound - Single vs Triple Hyaluronic Acid in Knee Osteoarthritis NCT07352540
- A RCT of Collagen Scaffold for the Repair of Talus Cartilage Injury NCT07917806
- Evaluation and Treatment of Patients With Connective Tissue Disease NCT00076830
- Fractional Radiofrequency With Streroids Versus Fractional CO2 Laser With Steroids in the Treatment of Keloids NCT07898605
- The Ultrasound-Guided Dextrose Prolotherapy in Ehlers-Danlos Syndrome Patients NCT05279937
- Regenerative Medicine for Joint Hypermobility and Instability NCT07688096
- Impact of Mesenchymal Stem Cells in Knee Osteoarthritis NCT03477942
- Absorbable Hemostatic Fluid Gelatin Trial NCT07830797
- Evaluation of Collagen-based Medical Device Treatment Combined With Physiotherapy in Subjects With Achilles Tendinopathy. NCT05464498
- Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage. NCT06163573
- Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery NCT07803250
- Corticosteroid Meniscectomy Randomized Trial NCT04641351
- Comparison Between Radiofrequency,Hydrodissection and Cryoneurolysis in Chronic Ankle Pain NCT07778589
- Comparison of Efficacy of Carbon Dioxide Laser With Subcision Versus Platelet-Rich Plasma Bio-Fillers With Subcision for the Treatment of Atrophic Acne NCT07752186
- Hyaluronic Acid Versus Platelet-Rich Plasma for Chronic Tendinopathy and Enthesopathy NCT07714811
ECM and collagen fillers in aesthetics
78 studies registeredcollagen filler OR biostimulator OR extracellular matrix aesthetic - Comparing Calcium Hydroxylapatite and Hyaluronic Acid for Interdental Papilla Reconstruction NCT07912294
- Prospective Evaluation of Recombinant Pbserum Plus® and Pbserum HA 2.0® in Aesthetic and Regenerative Bioremodeling NCT07908953
- Efficacy, Satisfaction, And Safety Of Cellulite Treatment Using Collagen Biostimulators NCT07908069
- Recombinant Collagen Freeze-Dried Fibre for Upper Facial Wrinkles NCT07897773
- Post-Menopause Skin Rejuvenation Study NCT07205744
- PLLA and CaHA-R for Aesthetic Rejuvenation NCT07202117
- Evaluation of the Effect of Smoking on Palatal Donor Site Tissue Profile in the Success of Connective Tissue Grafts NCT07777185
- Pre-marketing Trial to Assess Safety and Efficacy of 'Volumizing Filler Based on Hyaluronic Acid and Recombinant Collagen' NCT06336044
- Hyaluronic Acid vs I-PRF With Microneedling in Enhancing Peri-implant Soft Tissue NCT07750756
- Comparison of Efficacy of Carbon Dioxide Laser With Subcision Versus Platelet-Rich Plasma Bio-Fillers With Subcision for the Treatment of Atrophic Acne NCT07752186
- Homocysteic Acid Biostimulator for Photoaged Facial Skin NCT07722351
- Analysis of Safety and Tissue Interaction of Injectable Biosmulators NCT06993558
- A Synergistic Approach to Remodeling of Photodamaegd Skin: Exploring Laser-Assisted Biostimulator Delivery NCT07680426
- PIEZO-101 First-in-Human Safety and Proof-of-Concept Study NCT07671027
- Effect of Single Facial Acupuncture on Dermal Structure and Appearance Satisfaction NCT07664280
Regenerative breast reconstruction
14 studies registeredbreast reconstruction regenerative OR bioprinted breast - Regenerative Peripheral Nerve Interface for Prophylaxis Against Post-Breast Surgery Pain Syndrome NCT06580951
- LTFU of PCL Breast Scaffolds Used in 2021-BRV-004 NCT07383012
- Scaffold-guided Breast Implant Revision and Primary Breast Augmentation Surgery NCT07367698
- Scaffold-guided Breast Surgery NCT05437757
- A Study on Pain After Breast Reconstruction NCT06627582
- Regenerative Collagen Scaffold for Breast Volume Restoration After Breast Cancer Excision NCT07219316
- AlloMend Acellular Dermal Matrix Allograft in Pre-Pectoral Breast Reconstruction NCT06512259
- Retrospective Study of AlloMend Acellular Dermal Matrix (ADM) Allograft and Pre-Pectoral Breast Reconstruction NCT06853964
- Targeted Nerve Surgery for the Prevention of Post-Mastectomy Pain Syndrome: A Randomized Trial NCT07146009
- Implant-based Breast Reconstruction and Mastectomy With Fat Grafting After Breast Conserving Surgery and Radiotherapy NCT06119633
- Investigate Wound Healing, Aesthetics & Pt Satisfaction Post NAC Reconstruction Using a Decellularized Donor NAC Graft NCT05484934
- Treatment of Breast Cancer Related Lymphedema With Cell-assisted Lipotransfer NCT02592213
- Regenerative Tissue Matrix for Breast Reconstruction NCT01027637
- Study of Autologous Fat Enhanced w/ Regenerative Cells Transplanted to Reconstruct Breast Deformities After Lumpectomy NCT00616135
FDA 510(k) decisions for comparable devices
openFDA device API, read Nov 12, 2026. Collagen wound dressings and flowable matrices: 11 decisions in 3 years. CXU itself has no FDA decision: see the status above.
Accelagen Advanced Surgical Collagen Matrix, 1cc (CG-01AA); Accelagen Advanced Surgical Collagen Matrix, 2cc (CG-02AA); Accelagen Advanced Surgical Collagen Matrix, 3cc (CG-03AA); Accelagen Advanced Surgical Collagen Matrix, 5cc (CG-05AA); Accelagen Advanced Surgical Collagen Strip, 125x25x2mm (CG-125X25AA); Accelagen Advanced Surgical Collagen Strip, 250x25x2mm (CG-250X25AA) Berkeley Advanced Biomaterials Oct 22, 2026 Substantially Equivalent KGN
Promogran Prisma Collagen Matrix with ORC and Silver Solventum Germany GmbH Mar 13, 2026 Substantially Equivalent FRO
SurgiAid Collagen Wound Dressing (HA) Maxigen Biotech, Inc. Oct 16, 2025 Substantially Equivalent KGN
Bovine Dermis Collagen Dermal Matrix Collagen Matrix, Inc. Dec 19, 2024 Substantially Equivalent KGN
LUOFUCON® Silver Collagen Dressing Huizhou Foryou Medical Devices Co., Ltd. Dec 16, 2024 Substantially Equivalent FRO
LUOFUCON® Collagen Particles (Collagen Wound Dressing) Huizhou Foryou Medical Devices Co., Ltd. Apr 25, 2024 Substantially Equivalent KGN
Mineral Collagen Composite Bioactive Moldable Bone Graft Matrix Collagen Matrix, Inc. Mar 12, 2024 Substantially Equivalent MQV
HealiAid Dental Collagen Wound Dressing Maxigen Biotech, Inc. Nov 22, 2023 Substantially Equivalent OLR